Diagnostic criteria for multiple sclerosis: 2010 Revisions to the McDonald criteria
- Chris H. Polman
- Stephen C. Reingold
- Brenda Banwell
- M. Clanet
- Jeffrey A. Cohen
- MFMassimo Filippi
- Kazuo Fujihara
- Eva Havrdová
- Michael Hutchinson
- Ludwig Kappos
- Fred Lublin
- Xavier Montalbán
- Paul O’Connor
- Magnhild Sandberg‐Wollheim
- Alan J. Thompson
- Emmanuelle Waubant
- Brian G. Weinshenker
- Jerry S. Wolinsky
- MFMassimo Filippi
Annals of Neurology · 2011 · Wiley
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Abstract
New evidence and consensus has led to further revision of the McDonald Criteria for diagnosis of multiple sclerosis. The use of imaging for demonstration of dissemination of central nervous system lesions in space and time has been simplified, and in some circumstances dissemination in space and time can be established by a single scan. These revisions simplify the Criteria, preserve their diagnostic sensitivity and specificity, address their applicability across populations, and may allow earlier diagnosis and more uniform and widespread use.