Updated standardized endpoint definitions for transcatheter aortic valve implantation: the Valve Academic Research Consortium-2 consensus document (VARC-2)
- Arie-Pieter Kappetein
- Stuart J. Head
- Philippe Généreux
- Nick Piazza
- Nicolas M. Van Mieghem
- EH Blackstone
- TG Brott
- DJ Cohen
- Donald E. Cutlip
- Gerrit‐Anne van Es
- RT Hahn
- A J Kirtane
- Mw Krucoff
- S Kodali
- MJ Mack
- R Mehran
- Josep Rodes-Cabau
- Pascal Vranckx
- JG Webb
- Stephan; https://orcid.org/0000-0003-2653-6762 Windecker
- PSPatrick W.J.C. Serruys
- Martin B Leon
- (VARC)-2 Valve Academic Research Consortium
· 2012
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Abstract
The aim of the current Valve Academic Research Consortium (VARC)-2 initiative was to revisit the selection and definitions of transcatheter aortic valve implantation (TAVI) clinical endpoints to make them more suitable to the present and future needs of clinical trials. In addition, this document is intended to expand the understanding of patient risk stratification and case selection.