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F. von Delft
UnverifiedResearcher · ZA
Publications
11
Citations
4277
max across sources
Profile views
3
bot-filtered
Verification
L0
Overview
AI-generatedF. von Delft (RTX-00000182) based in ZA is a researcher on ResearchTrics. Lists research interests: computational drug discovery methods, enzyme structure and function, machine learning in materials science, nanoplatforms for cancer theranostics, x-ray diffraction in crystallography. Has 10 publications recorded, including "SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids" (2021), "Crystallographic and electrophilic fragment screening of the SARS-CoV-2 main protease" (2020), "Rapid Covalent-Probe Discovery by Electrophile-Fragment Screening" (2019).
An AI overview generated from this profile’s verified records — an interpretation, not a verified statement.
Research interests
- computational drug discovery methods
- enzyme structure and function
- machine learning in materials science
- nanoplatforms for cancer theranostics
- x-ray diffraction in crystallography
Publications (11)
- SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids273 cites
Cell stem cell · 2021 · DOI
- Structure, mechanism and crystallographic fragment screening of the SARS-CoV-2 NSP13 helicase261 cites
Nature Communications · 2021 · DOI
- Crystallographic and electrophilic fragment screening of the SARS-CoV-2 main protease547 cites
Nature Communications · 2020 · DOI
- Rapid Covalent-Probe Discovery by Electrophile-Fragment Screening349 cites
Journal of the American Chemical Society · 2019 · DOI
- CCP 4 i 2: the new graphical user interface to the CCP 4 program suite601 cites
Acta Crystallographica Section D Structural Biology · 2018 · DOI
- A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density336 cites
Nature Communications · 2017 · DOI
- Structural Basis for Cul3 Protein Assembly with the BTB-Kelch Family of E3 Ubiquitin Ligases299 cites
Journal of Biological Chemistry · 2013 · DOI
- Crystal structures of the endoplasmic reticulum aminopeptidase-1 (ERAP1) reveal the molecular basis for N-terminal peptide trimming261 cites
Proceedings of the National Academy of Sciences · 2011 · DOI
- Structure of the CaMKIIδ/Calmodulin Complex Reveals the Molecular Mechanism of CaMKII Kinase Activation312 cites
PLoS Biology · 2010 · DOI
- Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity326 cites
Nature · 2007 · DOI
- Crystal structure of fibroblast growth factor receptor ectodomain bound to ligand and heparin712 cites
Nature · 2000 · DOI
